Abstract:to conduct a pharmacodynamic research into HBV recovery capsule prepared with Common Leafflower about its anti-HBV and protective effect of liver cells.Methods:anti- HBV effect was observed through in vitro experiment in 2.2.15 cell line. Rat model of chronic liver injury was established using CCl4, and was divided to blank control group, CCl4 group, Yigan Ning Group, and Leafflower high-dose group, middle-dose group and low-dose group. Each group was subject to biochemical examination and histological examination to pathological changes in left hepatic lobe; peritoneal macrophage phagocytosis and content of haemolysin were determined in mice to observe the capsule’s effect on immune function.Results:maximum inhibition ratio of HBsAg and HBeAg were respectively 76.47%(d7) and71.43%(d5), moreover, HBV secretion and replication correlated positively with inhibitive action. When compared with CCl4 group, the leafflower group improved significantly in liver function, with less severe liver disorganization and fibroplasias; and was superior over various parameter value to Yigan Ning group. The leafflower group had similar effect as Levamisole, which was better than the blank control group: phagocytosis of peritoneal macrophage was reinforced, and content of haemolysin increased following sensitization induced by sheep red blood cell.Conclusion:HBV recovery capsule prepared with Common Leafflower had anti-HBV effect and protection of liver cells.