To investigate effectiveness and safeness of two preparations of Baohe: ultra-fine preparation vs. traditional decoction for functional dyspepsia (syndrome of stuffiness and fullness) and discover respective dose-effect relationship.Methods:A randomized trial was carried out on 60 patients who were respectively allocated to traditional decoction, or ultra-fine preparation (1/3、1/5 of original herbal dosage) for a course of 7 days to observe the patients’ conditions. Results:In the order of traditional decoction,1/3 group and 1/5 group, curative rates and effective rates for dyspepsia were respectively 15%,75% /15%,80% /5%,60%; curative rates and effective rates for food accumulation were 65%,90%/ 55%,85%/ 35%,75%, there was no significant difference of any parameters abovementioned between groups(P>0.05). Safeness-related abnormal change of clinical significance or adversary effect wasn’t found.Conclusion:Ultra-fine preparation of Baohe is effective for relieving clinical symptoms of functional dyspepsia at five-fold reduction of original herbal amount, and as effective as traditional decoction at the three-fold reduction of original herbal amount.