Abstract:To evaluate efficacy and mechanism of Yiqi Fumai Injection for acute cerebral infarction.Methods:Treatment group (n=41) was given Yiqi Fumai Injection, control group (n=51) given Danshen Injection. After 2-week treatment, comparison was made between two groups, i.e. efficacy, NFDS, Barthel index, hemorheology, lipids and function of vascular endothelial cells.Results:Total effective rate for treatment group= 82.9% compared with that of control group=70.7%, presenting significant difference (P<0.05). Neither group had obvious adverse effect.Conclusion:Yiqi Fumai Injection can stimulate recovery of neurologic defects, improve quality of life, which may be linked to improvement of function of vascular endothelial cells, regulation of lipid and hemorheology.