加味小陷胸汤干预湿热困脾型糖耐量受损30例临床研究
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上海市虹口区医学科研重大课题(0801-01)


Clinical Research of Modified Minor Chest Bind Decoction on IGT of Pattern of Dampness-heat Accumulating Spleen
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    目的:观察加味小陷胸汤干预湿热困脾型糖耐量受损,评价其疗效。方法:70例湿热困脾型糖耐量受损患者随机分为治疗组(n=33例)和对照组(n=37例),在生活方式干预的基础上,治疗组服加味小陷胸汤,对照组服二甲双胍片,观察治疗前后2组患者证候、血糖、胰岛素释放及其敏感性、胰岛素抵抗指数等改善情况。结果:治疗组患者在证候积分、血糖积分、胰岛素敏感性、体重指数、腰围、臀围与对照组比较有统计学意义。结论:加味小陷胸汤能显著改善患者中医临床症状,降低患者血糖积分,提高胰岛素敏感性,减轻体重,减小腰围,且无不良反应。

    Abstract:

    To observe and evaluate the therapeutic effects of modified Minor Chest Bind Decoction on impaired glucose tolerance(IGT) in the pattern of dampness-heat accumulating spleen.Methods:60〖BP(〗(和中文摘要人数不一致)〖BP)〗patients of the abovementioned syndrome were randomized to treatment group (n=30) and control group (n=30), respectively treated with the decoction and metformin, besides life style intervention. Changes in syndromes, glucose, insulin releasing, insulin sensitivity, insulin resistance exponent were observed.Results:Treatment group was significantly different from control group in syndrome score, glucose score, insulin sensitivity, BMI, waist line, hip line.Conclusion:The decoction can significantly relieve the dampness-heat syndrome, lower glucose, enhance insulin sensitivity, reduce weight and waist line, while having little adverse reactions.

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王亚平,史立华,顾江涛,张志银,朱艳,郑昕,庄敏之,张迪,武辉,周菲,郭兆玮,吴瑛,韩静,孙佳君,牛忆军.加味小陷胸汤干预湿热困脾型糖耐量受损30例临床研究[J].世界中医药,2010,5(5).

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  • 收稿日期:2010-06-30
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  • 在线发布日期: 2012-10-24
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