To observe effect of Combination of Acupuncture and Medicine on sudden deafness. Methods:Patients meeting the diagnosis criteria of sudden deafness, were randomized to control group (n=60) and treatment group (n=60). Treatment group took acupuncture and medicine plus Xueshuantong Injection; control group took Lipo-PGE1 and mecobalamin. Results:Total effective rate of treatment group was 91.67%, that of control group was 73.33% (P<005). Conclusion: Combination of Acupuncture and Medicine has definite clinical effect on sudden deafness.