复方丹参滴丸对急性心梗后早期心室重构的临床研究
DOI:
CSTR:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

基金项目:


Clinical Trial of Compound Danshen Dripping Pill on Ventricular Remodeling after Acute Myocardial Infarction
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:观察复方丹参滴丸对急性心肌梗死后心室重构的疗效。方法:90例冠心病患者,随机分为复方丹参滴丸治疗组和常规治疗对照组,治疗的第1、2周检测外周血白细胞(WBC),C反应蛋白(CRP),第4、6周检测心脏彩超指标,评价症状得分。结果:治疗第1周时,治疗组WBC和CRP显著下降;第2周时2组WBC比较无显著性差异,治疗组CRP低于对照组,差异显著;治疗第4周,治疗组左室舒张末期EDV、LVESV比较差异显著,2组LVDB、左室射血分数LVEDV比较差异不明显;治疗第6周,治疗组LVEF较对照组高,有显著性差异。结论:复方丹参滴丸可降低外周血WBC和CRP水平,减轻AMI后炎症反应,抑制AMI后LVDB扩张,降低LVEVD和LVESV,改善整体左室功能,且改善症状,具有抗心室重构作用。

    Abstract:

    To observe impact of compound Danshen dripping pill on ventricular remodeling after acute myocardial infarction. Methods:Ninety CHD patients were randomized to treatment group using compound pills, and control group using routine treatment. At week1 and week2, WBC and CRP were assessed. At week4 and week6, ECG was performed, and patients were rated according to clinical symptoms. Results:At week1, WBC and CRP of treatment group dropped drastically; At week2, treatment group had significantly lower level of CRP than control group, none significant differences of WBC; At week4, EDV and LVESV are significantly different between two groups, none significant differences of LVDB and LVEDV; At week6, treatment group had significantly higher LVEF than control group. Conclusion: Compound Danshen dripping pill could lower WBC and CRP levels, ameliorate subsequent inflammatory reaction, inhibit LVDB, lower LVEVD and LVESV, improve overall function of left ventricle, relieve symptoms and fight ventricular remodeling.

    参考文献
    相似文献
    引证文献
引用本文

林小端.复方丹参滴丸对急性心梗后早期心室重构的临床研究[J].世界中医药,2011,6(2).

复制
相关视频

分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2010-11-26
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2012-10-11
  • 出版日期:
文章二维码