中药分期治疗对兔桡骨骨折延迟愈合X线及血清ALP的影响
DOI:
CSTR:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

基金项目:


Impact of Chinese Medicine Treatment per Fracture Phase on X ray Score and ALP in Fractured Rabbits
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:观察中药分期治疗对兔骨折延迟愈合X线及血清碱性磷酸酶(ALP)的影响。方法:新西兰兔75只,无菌术下左侧桡骨中下1/3切除10mm后,除模型组外其余4组髓腔用骨腊封闭,分为治疗1组、治疗2组、治疗3组、模型组、延迟愈合模型组,每组15只。其中治疗2组术后按骨折分期第2天开始给药,治疗3组和治疗1组4周成模后给药,延迟愈合模型组和模型组术后第2天灌等容量的生理盐水,延迟愈合模型组成模后骨延迟愈合区注入自体红骨髓。术后第4周和8周检测血清ALP和拍摄线片。结果:第4周治疗2组血清ALP明显高于其他4组,差异极显著(P<0.01),第8周与延迟愈合模型组比较差异极显著(P<0.01),与模型组比较差异显著(P<0.05),治疗1组和治疗3组血清ALP与模型组比较显著下降(P<0.05),与治疗2组比较无显著性差异(P>0.05)。第4周末X线肉眼评分模型组极显著高于其他各组,第8周末治疗2组肉眼评分显著高于治疗1组和治疗3组及延迟愈合模型组(P<0.01),与模型组无明显差异(P>0.05)。结论:中药分期治疗明显提高了骨折X线肉眼评分,治疗2组血清ALP明显提高,中药组均有促进骨折愈合的作用。

    Abstract:

    To investigate impact of Chinese medicine treatment per phase on X ray film and serum ALP level in fractured rabbits. Methods:75 New zealand rabbits with fracture were equally divided to treatment group 1 to 3, model group (group 4) and delay union group(group 5). From Day2, group 2 was administered with Chinese medicine per fracture phase, group 4 and group 5 received same volume physiological saline, from Week4 group 1 and group 3 began treatment. Delay union group was injected with red marrow after establishment of modeling. At Week4 and Week8 following operation, serum ALP and X ray film were taken. Results:At Week4 ALP level of group2 was significantly higher than that of the rest groups (P<0.01), and kept at significant higher level in comparison with the model group and delay union group at Week 8. There wasn’t significant ALT difference between group 1 and group 2. At Week4 the model group had the highest score per X ray film, at Week8 the score of group2, higher than other groups, was not significantly different with the score of model group. Conclusion: Chinese medicine treatment per fracture phase can significant increase X-ray score and serum ALP level. The groups given Chinese medicine treatment can improve union of fracture.

    参考文献
    相似文献
    引证文献
引用本文

李天朗,唐志宇,王祖祥,付勇,温月.中药分期治疗对兔桡骨骨折延迟愈合X线及血清ALP的影响[J].世界中医药,2011,6(4).

复制
相关视频

分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2010-08-26
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2012-10-12
  • 出版日期:
文章二维码