To assess the therapeutic effect of Tongluo Fumai Drink on angina pectoris in female patients with diabetes and coronary heart disease. 〖WTHZ〗Methods:〖WTBZ〗Sixty eight patients were randomized, the treatment group (n=35) treated with Fumai Tongluo Drink and Western medicines, and the control group (n=33) treated with Western medicines only, for a course of 8 weeks. The relief of AP symptoms, ECG, blood glucose and lipid were observed. 〖WTHZ〗Results:〖WTBZ〗After treatment both groups improved in terms of symptom relief and ECG results. The treatment group showed greater improvements than the control group (P<0.05) regarding reducing seizure frequency, shortening duration of angina pectoris, lower levels of FPG and HDL C. 〖WTHZ〗Conclusion:〖WTBZ〗A combination of Chinese and western medicine has significant efficacy for angina pectoris in female patients with coronary heart disease and diabetes.