Abstract:The thought of “One” in Chinese medicine is a critical thinking model which links all the aspects of basic theories and clinic in Chinese medicine. “Qi as the origin” is at the core of the thought of “One”. The thought of “One” is the prerequisite of dialectic approach with Yin-Yang Theory, the guideline for basic theories of Chinese medicine, the basis of learning Chinese herbs and formulations. Dr.Lu Zhaolin points out that understanding the thought of “One” in Chinese medicine is the prerequisite and foundation of Chinese medicine learning.