Abstract:To explore the regulation effects of electroacupuncture(EA) with different frequencies and acupoints selection on weakened detrusor function, to provide scientific basis for acupoints and EA parameters selecting in clinical practice of acupuncture treatment for micturition disorders. Methods:One hundred New Zealand rabbits were randomly divided into control group, model group and EA groups (which were divided into 6 subgroups according to the acupoints and EA frequency selection: Zhongji 2Hz, Zhongji 100Hz, Sanyinjiao 2Hz, Sanyinjiao 100Hz, Quchi 2Hz, and Quchi 100Hz ). The model of weakened detrusor function was established by intravenous infusion of 0.05% scopolamine. Intravesical pressure was recorded through continuous cystometry and urination flow rate in each group was recorded.Results: 1) Groups of Zhongji 2Hz, Sanyinjiao 2Hz, Quchi 2Hz and Sanyinjiao 100Hz had significantly faster speed of initial urination than the model group ( P<0.05); 2)The micturition speed decrease with time in all the 2Hz EA groups were quicker than that in the model group ( P<0.05); 3)2Hz EA at different acupoints sped up the initial urination to different degree: Sanyinjiao = Zhongji > Quchi. Conclusion: 1)EA could significantly accelerate the urination speed in weakened detrusor function model; 2)The effects of 2Hz EA is better than 100Hz EA at accelerating micturition speed, and the effects are acupoins specific: EA at Sanyinjiao and Zhongji are better than EA at Quchi.