To observe the influence of Xuezhiqing granule on ApoB，ApoA1 and ApoB/ApoA1 of hypertension patients complicated with metabolic syndrome. Methods:According to the table of random number method，90 patients were divided into three groups，Atorvastatin Group，Blood fat clear Group and Combined treatment Group，with 30 cases in each group. Atorvastatin Group and Blood fat clear Group were given lipitor 10 mg/qd，blood fat clear grain 1 bag/tid respectively. Combined treatment group was given lipitor 10 mg/qd and blood fat clear grain 1 bag/tid. After a treatment for 8 weeks，the change of ApoB/ApoA1 ratio and other blood lipid parameters were observed before and after treatment. Results:After 8 weeks，the ratio of ApoB/ApoA1 and ApoB had declined significantly than before in 3 groups（P<0.01）. The ratio of ApoA1 had the trend of gradual growth both in Atorvastatin Group and Blood fat clear Group，but the difference was not statistically significant（P>0.05）. Among groups comparative differences also had no statistical significance （P>0.05）.But the ratio of ApoA1 and HDL-C had increased t in Combined Treatment Group，which had statistical significance for itself before and after treatment (P< 0.01)，it also had significant differences compared with other groups. Conclusion: Xuezhiqing granule can improve the symptoms of hypertension patients complicated with metabolic syndrome，reduce the ratio of ApoB/ApoA1，and will have more remarkable curative effect when combined with atorvastatin.