This paper summarized the background of building UCLA Information Center for Integrative East-West Medicine, which is a cooperation project between China and the United States. Through personally participating in the project in the United States and introducing the progress of the project, the author analyzed the important role of the information work playing on Traditional Chinese Medicine (TCM) culture dissemination overseas. UCLA Information Center for Integrative East-West Medicine serves as a communication platform for eastern and western medicine, it disseminates TCM culture for promoting the development of internationalization of TCM.