To observe the effect of Ginkgo Biloba Tablet (GBT) for mild cognitive impairment (MCI) in hyperuricemia patients. Methods:A total of 69 MCI and hyperuricemia patients from our medicine clinic were randomly divided into the control group (34 cases) and the treatment group(35 cases). Basic treatment of Zyloric， 0.1， 3 times a day was given to both groups. Besides， the treatment group was also given GBT 1 tablet each time， 3 times a day， and 3 months in all. The mini-mental state examination (MMSE) scores， clock drawing task (CDT) scores， MMSE efficacy， CDT efficacy， and dementia conversion rate were detected before and after treatment. Results:There was no significant difference in scores of MMSE and CDT between the two groups before treatment (P>0.05). Compared with before treatment， scores in the treatment group remarkably increased after treatment (P<0.01)， and the increases were higher than those of the control group (P<0.05). The total effective rate of MMSE and CDT of the treatment group (MMSE 74.3%;CDT 68.6%) all exceeded those of the control group (MMSE41.2%;CDT38.2%) (P<0.01). The dementia conversion rates after treatment (5.71%) were lower in the treatment group than in the control group(17.6%) (P<0.05). Conclusion:GBT used for 3 months can significantly improve the cognitive function of MCI patients， and also can lower the dementia conversion rate.