To observe the therapeutic effect of articular correspond acupoints combined with exercise therapy for the treatment of knee osteoarthritis.Methods:A total of 72 patients were randomly divided into treatment group and control group， 36 cases in each group. The control group was treated by needling xiyan， neixiyan， liangqiu， xuehai， dubizhong acupionts， and retained for 20 minutes， after that， taking the needles out. The treatmrnt group was treated by needling quchi， zhouliao， shousanli both sides， and retained for 20 minutes. During the retaining needle time， all patients had to try their best to flexor and extensor muscles of knees. All patients were treated once per day， and 20 times in all. “Knee Joint Function Assessment” defined by Japanese Plastics Association were selected to evaluate therapeutic effects of two groups.Results:After treatment， the pain of rest， walk， go up and down， and joint contracture in two groups was much better (P<0.01，P<0.05). Swelling was improved， but the difference was not statistically significant (P>0.05); comparing with the control group， except swelling， the differences of other three items’ scores in treatment group were statistically significant （P<0.01，P<0.05）.Conclusion:Articular correspond acupoints combined with exercise therapy can increase therapeutic effect for knee osteoarthritis， and it is a better therapy for this disease.