To observe the hyperalgesia of acupoints due to functional intestine disorder and detect the area of sensitized acupoints.Methods:We measured the pressure pain threshold (PPT) by electronic von fray. PPT was detected and compared among patients of functional intestine disorders and normal control on 13 acupoint related to intestinal disorders, 1cun, 2cun beside the acupioints, the control point in hemosegement and heterosegement.Results:1) the PPTs of acupoints ST 36, ST 37, ST 39, SP9; 1cun, 2cun beside the acupioints, the control point in hemosegement in patients decreased significantly compared with the control group(P<005); 2) the PPTs of acupoints LI11 and BL25 in patients of functional constipation decreased significantly compared with the control group(P<005).Conclusion:The results indicated that acupoints were not settled in a fixed point but in a certain area. Some acupoints could be sensitized as well as the sensitive area of acupoints were widen during pathological process.