To observe the effect of Ejiao soft capsule on anemia in mice.Methods:The mice were given fundus venous plexus phlebotomy to cause hemorrhagic anemia in animal models. The red blood cell (RBC), hemoglobin (Hb) and swimming time were observed after administration of the medicine, erythropoietin (EPO)in serum was measured by ELISA.Results:After triggering the hemorrhagic anemia model, the physical efficiency of the mice decreased, their swimming time reduced, RBC number and Hb dropped significantly, and EPO feedback relatively increased. Ejiao soft capsules strengthened animals' physical efficiency, improved abnormality of RBC and Hb, and EPO in serum were further increased.Conclusion:In this experimental condition, Ejiao soft capsule possesses anti-anemia function, it can improve the physical strength of the mice, increase RBC number and Hb content of the hemorrhagic anemia mice. These effects may be related to the increase of EPO levels in serum.