Abstract:TCM chronomedicine theory is an integral part of Chinese medicine. From a macro perspective, it reflects the rhythm of human physiological activities and organs activities. The modern gastrointestinal dynamics discovered some regularity related to time exist in gastrointestinal digestion, secretion and motility. The author made comparative analysis of the rhythmicity, explore relations between TCM Chronomedicine theory and gastrointestinal dynamics in order to guide clinic treatment.