To observe the therapeutic effect of Buchang Wenxin capsule combined with bisoprolol in treating ventricular premature contractions. Methods: Sixty five patients suffered from ventricular premature contractions were randomly divided into two groups. Patients in control group were given Bisoprolol apart from regular treatment on protopathy. Patients in observation group received additional treatment of Buchang Wenxin capsule apart from the same treatment as the control group. The treatment course was 30 days. The therapeutic effect of treatment and changes of ECG in two grouops were observed. Results: The total effective rate in control group and observation group were relatively 53% and 91%. There were significant differences between the two groups (P<0.05). Conclusion: Buchang Wenxin capsule shows satisfactory therapeutic effect in treating ventricular premature contractions with few side effects. It is worth generalizing.