Abstract:To observe the anti-inflammatory effect of Bin ing Capsule on syno-vial tissue of rats with acute gouty arthritis. Methods:After a successful modeling of 60 half male and half female Wistar rats, they were randomly divided into blank control group,model group, Western medicine group, Chinese medicine high dose group, Chinese medicine middle dose group, and Chinese medicine low dose group. They were all intervened by drugs for 7 days. The right ankle volume of rats and the level of Interleukin-1(IL-1) before modeling, after modeling and the end of treatment were measured. Besides, the synovial tissue of right ankles were put in routine HE staining after the death of rats, in order to observe and score the pathological synovial tissue through light microscopy. Results:Bining Capsule was beneficial to the repair of inflammation of damaged synovial tissue in rats, better than Western medicine group, and the Chinese medicine high dose group showed the best effect. Conclusion: Bining Capsule has significant anti-inflammatory effect in synovial tissue of rats model with acute gouty arthritis.