To briefly summarize the research progress on treatment of bedsores, so as to provide some reference information for proper and effective treatment of bedsores. Methods: This paper briefly introduced the treatment methods on bedsores after spinal cord injury with Chinese medicine, Western medicine and Integrative Medicine. Results: Western medicine treatment on bedsores after spinal cord injury usually used disinfectants or antibiotics so as to inhibit the growth of bacteria on bedsore wound surface, which showed good effectiveness but also hindered the tissue regeneration, slowed down the course of curing; external application of Chinese medicine worked to detoxify and generate flesh, activate blood circulation and dissipate stasis; combined application of western and Chinese medicine could treat both root and tip. Conclusion: Integrative medicine in treating bedsores after spinal cord injury could treat both root and tip with satisfactory effectiveness and fast wound healing, which deserves clinical generalization.