Diabetic patients with proteinuria-triggered by a variety of pathogenic factors in addition to diabetic nephropathy is difficult to treat. By analysing hundreds of clinical cases treated by Professor Lv Renhe and summarizing his academic experience, the author found that Professor Lv Renhe prescribed patients with various diet, physical exercise and medical treatment methods based on their own pathogenic factor and disease stage of diabetes with proteinuria. The author concluded that, in the treatment of diabetic patients with proteinuria, individualized treatment is better than general medical treatment.