To observe the therapeutic effectiveness and safety of intensive catgut embedding therapy in patients with STC. Methods:A total of 208 patients with STC were randomly divided into the treatment group and control group, with 104 cases in each group. The treatment group received intensive catgut embedding therapy, while the other received Maren Capsule. Clinical efficacy, related symptom scoring, marker residue were measured with a following-up of 6 months. Results: Cure rate and total effective rate for the treatment group were significantly higher (P<0.05). The symptom scoring of main clinical symptom in treatment group was statistically significant than before treatment (P<0.05). In terms of marker residue, treatment group changed significantly (P<0.05). Conclusion: With TCM theory basis, catgut embedding therapy combined with modern means of operation can significantly improve the clinical symptoms of constipation and promote bowel movements. As a combination of various methods, it has a variety of effects in patients. It is easy to operate, being less painful to patients, thus is worthy of spreading.