Using cluster statistical method, to analyze old Chinese medicine professor Ding Shuwen’s medication rules on treatment of hypertension. Methods: Effective or cured cases of hypertension in Professor Ding Shuwen’s outpatient clinic were selected and analyzed with EXCEL to count the frequency of used Chinese medicine prescription, and the number and frequency of herbs. Herbs that had been used with over 90% frequency were taken as highly frequently used herbs and cluster analysis was conducted using software SPSS to analyze them. Results: Chinese medicine prescriptions treating 183 cases of patients were selected and there were altogether 117 Chinese medicine herbs used, among which 42 were highly frequently used herbs. Five clustering prescriptions were concluded and analyzed. Conclusion: Clustering square analysis could to a certain extent reflect Professor Ding Shuwen’s clinical medication rules when treating hypertension.