Traditional apprentice education emphasizes practice which accords with the nature of traditional Chinese medicine and its regular developing pattern. It has obvious superiority on thinking methods and imparting knowledge of the TCM clinical skills. However, due to the lack of systematical theoretical learning, it would easily cause limits in knowledge structure. In the recent 60 years, modern college education has become a main channel to cultivate TCM talents. But because of the tendency of placing too much on theories while ignoring practices, it also limits the cultivation of excellent TCM talents. Our institute carried out TCM apprentice education reform pilot work on the background of special education of TCM since 2005. We have combined TCM apprentice education and college education to bring about integrated development of the TCM education which has made some gratifying achievements.