Abstract:To set up diagnosis methods of mini swine coronary heart disease (CHD) angina model of phlegm-stasis syndrome type. Methods: Mini swine were randomly divided into the control group and the model group, fed with common forage and high fat forage respectively for 14 weeks and the coronary left anterior descending branch in the model group was injured by balloon intervention technique after 2-week feeding to establish CHD model. The model establishment and its physiopathology indices were evaluated by examinations on body surface electrocardiograph (BS-ECG), body mass index (BMI), pulse conditions, tongue pictures, noninvasive heart function monitor, arteria femoralis pulse wave. Using ECG as the principal index, BMI as secondary index, tongue picture as tongue manifestation, and arteria femoralis pulse wave as pulse manifestation, giving scores based on above criteria. Results: Principal symptoms, accompanied symptoms, tongue picture and pulse condition of the model group swine were all significantly changed compare with those in the control group respectively. Tongue picture of model group showed lower R value and red saturation level, the pulse wave revealed h3/h1 difference after 2 weeks. Conclusion: The method of objective standardization scoring for TCM syndrome shows a better stability in the study of mini swine CHD model of phlegm-stasis syndrome type. The normalized tongue picture collection method contributes to evaluate the changes of disease, while the pulse wave pattern method in evaluating the pulse condition of compound factor animal model still needs to be investigated.