The cause of hypertension is due to imbalance of ying and yang in human body, causing disorder of qi and blood, abnormal blood circulation and all can be pointed to the cause of blood stasis. Therefore hypertension is divided into five syndrome patterns of blood stasis such as blood stasis and stagnation of liver qi whose treatment prescription is “decreasing hypertension No. 1” which aims at activating blood, dissipating blood stasis, and smoothing liver qi. Two hundred patients were included in the treatment group, and 200 patients were put in the observation group. The total effective rate of lowering blood pressure in treatment group was 96.85%, total syndrome effective rate was 93.50%. The total effective rate of lowering blood pressure in control group was 87.70%, total syndrome effective rate was 89.50%. There were better results in the treatment group. Besides, the lab results of microcirculation of bulbar conjunctivae, lipemia, hemorheology, plasma, endothelin-1 and serum-nitrogen were all improved after treatment, and more obvious changes were seen in treatment group. It showed that the method of activating blood and dissipating blood stasis to treat hypertension not only supports the theoretical evidence, but also manifests practical significance. Compared with conventional therapies, this method decreases blood pressure obviously with satisfactory, stable and persistent therapeutic effect, which is worth general application.