To evaluate Wulong Granule in improving allergic rhinitis with Lung and Spleen Qi Deficiency Syndrome. Methods: This is a randomized, double-blind single simulation, parallel-controlled, multi-center clinical study conducted at 10 hospitals, enrolling 585 patients of allergic rhinitis with Lung and Spleen Qi deficiency syndrome. There are three groups, 351 patients in experimental group took Wulong granule, 117 patients in the positive control group took Xinqin granule and placebo of Wulong granule, 117 patientst in placebo control group took placebo of Wulong granule. The duration of study treatment is 7 days, patient performed clinical visit on day 4 and day 8. Results: Individual indicator score of nasal itching, sneezing and other symptoms in positive control group and experimental group were superior to placebo group. A statistically significant difference between them was shown. Conclusion: Wulong granules have good clinical efficacy and safety in treating allergic rhinitis with Lung and Spleen Qi deficiency syndrome.