To observe the effect of Chinese herbal fumigant of Cuyuxunxi prescription on patients after anal fistuletomy. Methods：One hundred and forty four patients after anal fistuletomy were divided into 4 groups randomly with 36 patients in each group. Group One gave patients sitting bath with Chinese herbal fumigant of Cuyuxunxi prescription with concentration of 125 mL：2 000mL for10 minutes; patients in Group Two received sitting bath with Chinese herbal fumigant with concentration of 125 mL：3 000 mL for 20 minutes; patients in Group Three were given sitting bath with Chinese herbal fumigant with the concentration of 125 mL：2 000 mL for 20 min; Group Four gave patients sitting bath with Chinese herbal fumigant with concentration of 125 mL：3 000 mL for 10 minutes. After 14 days of treatment，the pain，pruritus，turgescence，effusion and healings of the cuts were observed. Results：Long time treatment with low concentration of Chinese herbal fumigant showed significantly good results in terms of postoperative pain，pruritus，turgescence，effusion and healings of the cuts (P<0.05). Conclusion：Long time treatment with low concentration of Chinese herbal fumigant of Cuyuxunxi prescription can relieve the pain，pruritus，turgescence，effusion after anal fistuletomy and promote the healings of the cut.