溃疡性结肠炎灌肠液治疗溃疡性结肠炎的临床疗效观察

doi:10.3969/j.issn.1673-7202.2013.12.016

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溃疡性结肠炎灌肠液治疗溃疡性结肠炎的临床疗效观察
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                        10.3969/j.issn.1673-7202.2013.12.016
                    
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基金项目:北京市中医药科技基金项目(编号：2008-87)

Observation on Clinical Curative Effect of Kuijie Enema in Treating Ulcerative Colitis

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目的：观察中草药灌肠对溃疡性结肠炎的临床疗效。方法：将60例溃疡性结肠炎患者给予自拟灌肠液治疗，检测血清细胞因子水平白介素1β(Interleukin-1β，IL-1β)、肿瘤坏死因子(Tumor Necrosis Factor-α，TNF-α)、一氧化氮合酶-3(内皮型)(Nitric Oxide Synthase-3，Nos-3/eNos)的变化趋势以观察中草药液灌肠对溃疡性结肠炎的临床疗效。结果：治疗1个疗程后，总有效率达93.33%，IL-1β平均提升了19.7%，TNF-α平均降低了14.7%，Nos-3/eNos平均降低了20.8%。结论：溃疡性结肠炎灌肠液在防治溃疡性结肠炎方面，疗效可靠，使用方便，造价低廉，值得临床推广。

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To observe the clinical curative effects of Chinese herbal medicine enema in treating ulcerative colitis. Methods：Sixty patients with ulcerative colitis were given the treatment of self-made enema. They were given the detection of serum cytokines，such as IL-1 β，TNF- α and Nos-3/eNos to observe the clinical curative effects of the Chinese herbal medicine enema on ulcerative colitis. Results：After a course of treatment，the total effective rate was 93.33%. The level of IL-1β was promoted by 19.7% on average，and the level of TNF- α was reduced by an average of 14.7%. The level of Nos-3/e Nos was decreased by 20.8%.Conclusion：In the treatment of UC，Chinese medicine Kuijie enema shows the advantages of reliable curative effect，easy application，and low cost，which is worth of clinical application.

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任毅张振忠赵洪波马树梅李远梁斌强刘宁州豆小妮万照良文华.溃疡性结肠炎灌肠液治疗溃疡性结肠炎的临床疗效观察[J].世界中医药,2013,8(12).

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收稿日期:2013-11-28
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在线发布日期: 2013-12-30
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