To optimize the grinding and extracting process for Radix Pueraria Boiling Powder.Methods：Three different sizes of particles were prepared，HPLC method was used for the determination of the content of Puerarin.Yield of dry extract and the content of puerarin were the referent indexes to select the optimum particle size，and the decoction process was optimized by single factor test with boiling time，amount of water and boiling times as factors.Results：At least 80% of the particles having particle size between 2 and 0.18 mm was the optimum size.The optimal conditions of decoction process were 20-fold solvent，boiling 20 minutes，1 time.Conclusion：The optimized grinding process is easy and suitable in mass-production; the decoction process is user-friendly and suitable in clinical.