中药舒鼻喷剂与西药鼻喷剂治疗过敏性鼻炎31例临床观察
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Clinical Observation of 31 Allergic Rhinitis Patients treated by TCM Shubi Spray and Western Medicine Nasal Spray
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    摘要:

    目的:通过观察中药鼻喷剂与西药鼻喷剂对于治疗过敏性鼻炎的疗效比较,探讨中药鼻喷剂的临床应用价值。方法:选取过敏性鼻炎患者共31例,采用单盲试验,用外观相同的喷罐分别装入中药鼻喷剂及西药鼻喷剂,给予受试者,嘱咐受试者固定一个鼻孔喷中药液,另一个鼻孔喷西药液,每天3次。1周回诊检查1次,实验时间共计两周。检查方法分两部分:鼻腔摄影记录,填写疗效评估表。结果:本次观察病例共31例,有3例失联或中途放弃,共实际观察28例。中药喷剂疗效优于西药喷剂供16例,占57%。中药喷剂疗效等同西药喷剂共7例,占25%。中药喷剂疗效劣于西药喷剂共2例,占7%。中药喷剂无效者共3例,占11%。西药有11例无效,占39%。鼻腔摄影显示中药喷剂经两周持续使用后,无1例出现不良反应。结论:中药鼻喷剂治疗过敏性鼻炎疗效确切,而且无不良反应出现,具有良好的临床应用价值。

    Abstract:

    To compare the treatment effect between Levocabsitine and Shubi Spray for the allergic rhinitis, and investigate the clinical application value of TCM nasal spray.Methods:Thirty-one patients were participated in the single-blind study, each patient was given one bottle of Shubi Spray and one bottle of Levocabsitine, each was used for one nasal cavity, 3 times a day, 2 weeks.At end of each week we used micro-camera to observe the nasal mucosa.Results:3 patients lost to follow up or withdrew the study prematurely, 28 patients completed the study.16 patients reported superior efficacy of Shubi Spray to Levocabistine (57%).7 patients reported no significant difference of Shubi Spray and Levocabistine (25%).2 patients reported inferior efficacy of Shubi Spray to Levocabistine (7%).3 patients felt the Shubi Spray have no effect (11%), compared to 11 patients who felt levocabstine have no effect (39%).No adverse reaction was observed or reported.Conclusion:The Shubi Spray was effective for relieving clinical symptoms of allergic rhinitis, and its safety was assured, therefore it has good clinical application prospect.

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张 肇 宇.中药舒鼻喷剂与西药鼻喷剂治疗过敏性鼻炎31例临床观察[J].世界中医药,2014,9(01).

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  • 收稿日期:2013-09-28
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  • 在线发布日期: 2014-01-20
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