To observe the effects of different extractions of Suanzhiqing capsules on rats with acute gouty arthritis. To study on the anti-inflammation mechanism and effect on cartilage damages in acute gouty arthritis rats. Methods： Water extractions and ethanol extractions of Chinese medicines Suanzhiqing capsules were administrated intragastrically to the model rats . Seven days later, the rats were given uric acid sodium to cause acute gouty arthritis. And after 9 hours and 12 hours, eight rats were randomly selected each time in each group to measure the diameter of the ankle joint, and the contents of IL-1and IL-1Ra through Elisa method on the blood taken from inferior vena cava. Results： The level of IL-10 and IL-1Ra in the medicine groups were increased to some extent compared with the control group. The most significant increase was observed in the water extraction group. Conclusion： Suanzhiqing capsules can raise the level of IL-10 and IL-1 to cure inflammation and protect articular cartilage, especially with its water extraction group.