To study the effect of blood stasis syndrome on the onset rate of AAD. Methods： Retrospective study was conducted on the 216 patients admitted to ICU in our hospital from 2012 February to 2013 February and treated with antibiotics, in the aspects of onset rate of AAD on patients with and without blood stasis syndrome, the percentage AAD was taking among the syndrome patterns of AAD, as well as the mechanism of AAD complicated with blood syndrome. Results： The onset rate of AAD on blood stasis patients treated by antibiotics was 45.26%, which was higher than that of the non-blood stasis patients (P<0.05). Among all the syndrome patterns of AAD, blood stasis took 29.63%, which was after the spleen deficiency accompanying phlegm. Among the pathological causes of AAD complicated with blood stasis, the phlegm and blood stasis took the percentage of 54.17%. Conclusion： Patients with blood stasis especially complicated with spleen deficiency are more easily to get AAD. Blood stasis is the most important syndrome in AAD syndrome patterns. The pathological mechanism of AAD accompanying with blood stasis is phlegm and blood stasis.