To analyze and summarize the characteristics of TCM syndromes and treatment in male patients with infertility attributing to non-liquefaction semen based on TCM literatures review. Methods： Literatures on TCM syndrome of male patients with infertility attributing to non-liquefaction semen published from 2002 to 2012 were retrieved from CNKI database. The selected literatures were recruited in a new database. The characteristics of TCM syndromes and treatment in male patients with infertility were further analyzed and summarized. Results： Among the recruited 39 literatures, 19 articles were on syndrome differentiation and treatment, 15 articles were on special prescription treatment, 5 articles were on integrated treatment of CTM and western medicine. In 19 articles on syndrome differentiation and treatment, top 5 of syndrome type with frequency were as follows： deficiency of kidney yin, damp-heat diffusing down, deficiency of kidney yang, phlegm-accumulation stasis, deficiency of kidney yin and damp-heat diffusing down. The given treatment was considered as the syndrome differentiation and the complex pathogenesis. The high frequency of traditional Chinese medicine category in the 15 articles on TCM special prescription and 5 articles on integrated TCM and western medicine were as follows, nourishing yin and clearing heat, cooling blood to remove blood stasis, clearing heat and removing dampness, resolving hard lump. Among all the prescriptions, it indicated that the complex mechanism for infertility male attributing to non-liquefaction semen targeted on notifying yang. The characteristics for the treatment to combine differentiation of TCM sydrom and diseases revealed that it is necessary to reinforce insufficiency and reduce excessiveness, keep balance between Yin and Yang. Conclusion： The mechanism of male infertility attributing to non-liquefaction semen is complex, mingled with excess and deficiency syndromes. The scheme of treatment on this disease is determined on the situation of patients. It is necessary to weigh and consider balance between insufficiency and excessiveness.