西替利嗪联合玉屏风散治疗过敏性鼻炎疗效分析
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Analysis on Therapeutic Effect of Cetirizine Combined with Yupingfeng San in Treating Allergicrhinitis
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    摘要:

    目的:探讨过敏性鼻炎(AR)的治疗方法及西替利嗪联合玉屏风散对AR的疗效。方法:采用随机数字表法,将120例AR患者分为2组,每组60例,对照组口服西替利嗪1次/d,10 mg/次;观察组在对照组基础上,水煎服玉屏风散1剂/d,早晚各服1次,共400 mL。连续用药14 d为1个疗程,2个疗程后比较2组临床疗效、临床症状消失时间、症状评分及不良反应情况等。结果:观察组治疗1个疗程和2个疗程后总有效率分别达到83.33%和95.00%,显著高于对照组;鼻塞、鼻痒、喷嚏和流涕症状消失的时间分别为(6.12±2.43)d、(7.65±2.59)d、(3.27±1.86)d和(3.11±1.42)d,均显著早于对照组各症状的消失时间(P<0.05);症状体征总积分为(2.57±1.04)分,显著低于对照组(3.86±1.20)分(P<0.05);总不良反应率和复发率仅为6.67%和11.67%,显著低于对照组(P<0.05)。结论:西替利嗪联合玉屏风散治疗过敏性鼻炎,起效快,效果好,不良反应少,临床疗效确切。

    Abstract:

    To investigate the curative effective of Cetirizine combined with Yupingfeng San in treating allergicrhinitis (AR). Methods: One hundred and twenty patients with AR were divided into two groups according to the random number table and there were 60 cases in each group. The control group applied daily oral administration ofhttp://dict.baidu.com/s?wd=%20profess%20to%20be%20convinced - # cetirizine 10 mg/ time. Patients in the observation group were given 400 ml of Yu Ping Feng San in the mornings and evenings except from the same treatment as the control group. The clinical efficacy, disappearance time of clinical symptoms, symptom score and adverse effects of the two groups were compared after 2 courses of treatment. Results: The total effective rate of the observation group after one treatment course and two treatment courses were 83.33% and 95% respectively, which were both significantly higher than those of the control group. The disappearance time of nasal congestion, nasal itching, sneezing and runny nose symptoms in the observation group were (6.12 ± 2.43) d, (7.65 ± 2.59) d, (3.27 ± 1.86) d and (3.11 ± 1.42) d respectively, which were all significantly shorter than those of the control group (P<0.05). The overall symptom score in the observation group was (2.57 ± 1.04) points, significantly lower than that of the control group (3.86 ± 1.20) points (P<0.05).The total adverse reaction rate and recurrence rate was only 6.67% and 11.67% in the observation group, significantly lower than that of the control group (P<0.05). Conclusion: Cetirizine combined with Yuping Feng San could significantly improve the symptom of allergicrhinitis and reduce the adverse reactions and the clinical curative effect is definite.

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陈 莉 陈显文.西替利嗪联合玉屏风散治疗过敏性鼻炎疗效分析[J].世界中医药,2014,9(07).

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  • 收稿日期:2013-08-15
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  • 在线发布日期: 2014-07-17
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