According to the herbalogical study of Tibetan medicine Mirabilis Himalaica and comparative study with Mirabilis Jalapa， to figure out the original plant of Mirabilis Himalaica and solve its species problem. Methods： Herbalogical study of ancient works combined with analysis of modern achievements were conducted， and then the difference and similarities between Mirabilis Himalaica with Mirabilis Jalapa were compared. Results： According to textual research， the ancient Mirabilis Himalaica and current Mirabilis Himalaica shall be completely consistent. And Mirabilis Himalaica shall be classified as Oxybaphus. Conclusion： The traits of medicinal parts of Mirabilis Himalaica and Mirabilis Jalapa are almost similar， but the difference of their properties and flavors is obvious， so they could not be mixed up for application.