To observe the curative effect of Qi Lang Mixture for treating the chronic functional constipation (CFC) and screening the optimum syndrome，and make efficacy comparison with Maren soft capsules.Methods：188 CFC patients were randomly divided into two groups：the treatment group(n=100) and the control group(n=88).The treatment group was treated by Qi Lang Mixture.The control group was treated with Maren soft capsules.After eight-week treatment，we made a comparison between the two groups using symptom scoring and total scoring of.Results：The total effective rate of the treatment group was 90.0%; the total effective rate of the control group was 71.6%.The total effective rate of the treatment group was significantly higher than the control group(P<0.05).Compared with the control group，the symptom score of the treatment group showed significant improvement (P<0.05).Conclusion：Qi Lang Mixture has significant efficacy for treating chronic functional constipation，especially good at treating the pattern of Qi and Yin (blood) deficiency.