To investigate the effect of Chinese medicine sequential treatment patterns and consolidation therapy patterns on overall survival time and median survival time of patients with stage III / IV gastric cancer. Methods： Seventy two patients who were diagnosed as stage III/IV gastric cancer and received treatment in March 2009 to September 2010 in our hospital were randomly divided into treatment group (n=36) and control group (n=36). Patients in the treatment group were given sequential TCM treatment and patients in the control group received consolidation TCM therapy. The overall survival after treatment and median survival situation were observed. Results： The median OS of the treatment group was 32 months, which was significantly better than the 19 months of the control group (P<0.05); the median OS of patients who took decoction in early stage was 24.1 months, which was significantly better than the 14.3 months of those took decoction later, and there was statistically significant difference (P<0.05); MST of treatment group was 17.2 months, which was significantly better than the 6.9 months in the control group, and the difference was also statistically significant (P<0.05). Conclusion： Although the combination therapy may prolong survival in gastric cancer patients, but sequential treatment of can better prolong the survival of patients, and therefore it is worthy of further applications.