Alzheimer’s disease is a primary central nervous system disease，often seen in the senile and presenile.This paper discusses the pathogenesis and treatment methods from the releasing orifices and strengthening brain.viewpoint of traditional Chinese medicine.Alzheimer’s disease is manifested as a deficiency syndrome，especially Qi-blood deficiency.Although it is a disease with the brain，the cause is closely related to to heart，liver，spleen，kidney and brain. According to the different syndromes，Buzhong Yiqi Decoction is used for strengthening the spleen and replenishing qi，Six Ingredient Rehmannia Decoction is used for tonifying the kidney essence，Shenling Baizhu powder is used for expelling phlegm and expel pathogen，Guipi Decoction is used for enriching the blood and qi，Jiawei xiaoyao pill is used for soothing liver and invigorating spleen and phlegm，Tongqiao huoxue Decoction to invigorate the circulation of blood and Qi obstruction.These treatments achieve the purpose of releasing orifices and strengthening brain.