Arrhythmias is a type of disease caused by abnormal electrical activity of the heart rate or rhythm.Active ingredients extracted from Chinese herbal medicines such as alkaloids、flavonoids、saponins、volatile oils、esters，terpenes and other active ingredients can impact the Na+、Ca2+ and K+ channels，so the action potential and effective refractory period can be extended，in that way to treat arrhythmias caused by adrenaline，calcium chloride and ischemic reperfusion.This mechanism of these active ingredients were reviewed to provide solid theoretical foundation for further research of anti-arrhythmias drugs.