Abstract:Trying to explain the constitution, physiology and pathology of human beings according to the newly reconstructed structural drawing of Qi-Yin and Yang- Five Elements in TCM. Methods: The structural drawing was created by integrating the meaning contained within the article of The Explanation for the Tai Ji Diagram written by Dunyi Zhou with the structure of DNA double helix. Results: Reconstructed a structural model of Qi-Yin and Yang-the Five Elements double helix. Conclusion:A new and intuitive structural drawing was reconstructed by integrating all the Qi, Yin and Yang and the Five Elements. And it can be used to explain the constitution, physiology and pathology of human beings.