Gouty nephropathy is a syndrome of intermingled deficiency and excess, it involves the spleen and kidney deficiency, turbid dampness, and blood stasis. In the acute stage, gouty nephropathy is manifested by damp and hot blood, in the stable period, is manifested by Spleen and kidney qi deficiency. Chinese Herbal Prescription（YiShenXieZhuo Decoction）is a Clinical prescriptions formulated by Professor Chen Yiping, who is the famous nephropathy expert in our hospital. The prescription has been formulated to the etiology and pathogenesis of gouty nephropathy. It is effective for tonifying kidney and spleen, promoting blood circulation, eliminating dampness, thereby treat gouty nephropathy effectively. For reference please find below interim results of an ongoing clinical trials and 3 case studies.