To observe clinical effect of rotation-traction manipulation combined with cervical vertebra rehabilitation exercise treating nerve root type of cervical spondylosis, so as to promote the popularization and application of the technique. Methods: One hundred and twelve patients were divided into treatment group (n=56) and control group (n=56) in multicenter central randomization. Patients in treatment group were given rotation-traction manipulation with cervical vertebra rehabilitation exercise and the others group only applied with rotation-traction manipulation treatment. The curative effect of two groups and the relapse within three months were observed. Results: Both groups obviously improved overall symptoms and signs of patients with nerve root type of cervical spondylosis. There was no significant difference in terms of the curative effect between the end of the treatment and a month after treatment. But three months after treatment, the total effective rate of treatment group was 94.44%, and that of the control group was 83.64%, which showed statistically significant difference (P<0.05). The recurrence rate in treatment group one month after treatment was 2%, and 3 months after treatment was also 2%; the recurrence rate in control group on month after treatment was 4%, and 3 months after treatment was 10%. Conclusion: Both groups for the treatment of nerve root type of cervical spondylosis have good curative effect, and treatment group on the whole, has more durable curative effect with lower recurrence rate and its suitable for primary hospitals. Cervical vertebra rehabilitation exercise might have some effect for the prevention of recurrence on nerve root type of cervical spondylosis.