Cui Shangzhi (1924—1989) was a very famous integrative physician in China. As an integrative pioneer, he started the research on the treatment of blood activating and stasis removing. He devoted all his life to the integrative medicine. Dr. Cui specialized in treating coronary heart disease (CHD) combining Chinese herbs with western medicine. He invented a Chinese herb formula called guanxin 1 with his colleagues, and did a series of clinical and basic researches on it, through which he proved the effect of guanxin 1 on treating CHD and expounded its therapeutic mechanism. Dr. Cui advocated that the syndrome differentiation should combine Chinese medical disease differentiation with syndrome differentiation according to western medical diseases. In Nei Jing, CHD is considered as Xin Bi, and Dr. Cui differentiated the syndromes of Xin Bi into two main syndromes and eight subordinate syndromes according to CHD and its morbidity.