To explore the efficacy and mechanism of Tongxuekang capsule on postpartum hemorrhage. Methods： 1）The pregnancy incomplete abortion model was built by giving mifepristone and misoprostol to the 7-day pregnant rats and Tongxuekang capsule was applied to intervene. The uterine smooth muscle activity in vitro of rats and pathological and histological changes of uterusin each group were observe and recorded. 2）The mice tail blood method was applied to observe the effects of Tongxuekang capsule on coagulation time in mice. 3）The auricle swelling model in mice and granuloma induced by cotton ball model in rats was adopted to observe the anti-inflammatory effects of Tongxuekang capsule. 4） The blood stasis model in rats built by adrenal in subcutaneous injection and ice water stimulation was made to survey the effects of promoting blood circulation and removing blood stasis of Tonxuekang capsule. Results：Tongxuekang capsule could not only enhance the intensity of uterine smooth muscle contraction of the early pregnancy incomplete abortion rats and promote the discharge of residual embryo sac, but also decrease viscosity of whole blood and plasma blood in stasis model rats and shorten the clotting time in mice. It could also control the mice auricle swelling and cotton ball granuloma of rats caused by xylene. Conclusion： Tongxuekang capsule has the function of treatment of postpartum hemorrhage and the mechanism of it may be related to enhancing uterus contraction strength of the abortion in rats, promoting the discharge of villi residue in uterine cavity or decidual tissue, shortening the clotting time, inhibiting inflammation and so on.