To evaluate the efficacy and safety of Traditional Chinese medicine treatment of hyperthyroidism. Methods：computer retrieval literature about clinical research of traditional Chinese medicine in the treatment of hyperthyroidism，selected RCT &CCT researches in human body comply with the requirements from the establishment to 2014 since January，Meta analysis was performed to assess the quality of literatures，by using RevMan 5.2 software（download from Corhrane collaboration network），using Cochrane manual to evaluate the articles. Results：in the 16 randomized controlled trials involving 702 patients were included，661 patients were effective，controlled group involving 590 patients were included，462 patients were effective. Meta analysis showed that the traditional Chinese medicine in the treatment of subacute thyroiditis and simple western medicine in the treatment of total effective rate（cure & better），the difference was statistically significant［OR=0.22，95％CI（0.15，0.33），Z=7.76，P< 0.01］.Conclusion：the effective rate and cure rate is better than pure western medicine group using traditional Chinese medicine treatment of subacute thyroiditis.