Primary liver cancer is one of the diseases that have the highest incidence and mortality rate.Moxibustion has a good effect on enhancing immune ability,especially in the treatment of tumor and cancer belonging to accumulation type based on the theory of Traditional Chinese Medicine.This paper summarized related literatures about the clinical and experimental studies on moxibustion in the prevention and treatment of primary liver cancer in recent years.It analyzed the effect of moxibustion in suppressing tumor growth,relieving clinical symptoms,improving side effects of chemotherapy and radiotherapy and enhancing immunity.Moxibustion showed definite effect in preventing and curing primary liver cancer.But we need to strengthen the systematical research,enhance clinical research quality,and further clarify its mechanism in the future researches.