To observe clinical curative effect of steamed panax notoginsengfor treating leukopenia after chemoradiotherapy. Methods: A total of 74 leukopenia patients were randomly divided into observational group and control group. After chemoradiotherapy, the observational group was treated with steamed notoginseng powder, the control group were treated with compound e-jiao syrup. The course of treatment was 2 chemotherapy cycle. We compared the clinical effect and WBC of these two groups. Results: The total effective rate of observational group was 75.67, higher than 59.46% of control group. The white blood cell count of observational group was significantly different before and after therapy, and there was a significant difference of WBC between these two groups (P<0.05). Conclusion: Using steamed panax notoginseng powder on patients afterchemotherapy to treat leukopenia is applicable in clinical use.