Functional gastrointestinal disease is one of the most common diseases of digestive outpatient service. It received extensive attentions of scholars both at home and abroad because of its high incidence, needing repeatedly visits and affecting the quality of lives in patients with different degrees. Its etiology and pathogenesis has not been fully elucidated, mainly related to changes in gastrointestinal disorders, visceral sensitivity, brain-bowel axis, immune and psychosocial factors, etc. The effect of western medicine with symptomatic treatment is not very precise. TCM can particularly expound pathogenesis of the disease with its unique theoretical system. It considers that FGIDs is closely related to the liver and spleen and its basic pathogenesis is stagnation of liver qi and spleen deficiency. Therefore, the rule of regulating liver and spleen method for curing functional gastrointestinal diseases can often achieve well curative effects.