To observe the clinical efficacy of Erjia Xiaozheng decoction in the treatment of Idiopathic pulmonary fibrosis with qi deficiency and blood stasis syndrome. Methods: Fifty-four subjects with IPF were randomly divided into 2 groups according to treatment sequence: 26 subjects in control group were treated with Jinshuibao capsule, 4 capsules once, 3 times a day; 28 subjects in treatment group were treated with Jinshuibao capsule and Erjia Xiaozheng decoction.The therapeutic course was 6 weeks. Results: The symptom integral, diffusion capacity for carbon monoxide of the lung(DLCO), six-minute walking distance were improved more significantly in treatment group than in control group(P<0. 05).But there was no significant difference between the two groups in TLC and FVC. Conclusion: Erjia Xiaozheng decoction is effective for IPF with Qi deficiency and Blood stasis syndrome. The decoction may improve lung diffusing function and activity endurance.